There are phases of drug experimentation, misuse, and addiction that can make it difficult to tell whether someone has opioid use disorder or is headed in that direction. Certain factors are important to consider, especially age, medical history, and any ongoing mental health conditions such as depression and anxiety. Genetics and environment also play a role in determining how susceptible a family member is to addiction, so bearing those in mind along with noticing distinct changes can help determine whether a loved one is battling opioid addiction and may need help.